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The rationale for utilizing different conventional B12 supplement at each center, for comparison with Sucrosomial B12, was to ensure the reproducibility of study outcomes amidst the variability in B12 formulations

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Using too little water creates a solution so concentrated that a single unit on the syringe contains several milligrams

Eligible studies included randomised controlled trials, cohort, and case-control studies assessing B12 supplementation efficacy via oral, sublingual, or IM administration routes