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However, it is essential to use it in appropriate amounts, as excessive intake may lead to adverse effects

The cardiovascular safety profile of GLP-1 agents is well-established from SUSTAIN and REWIND trials, which documented reduced cardiac events in patients with type 2 diabetes

As GLP - 1 drugs gradually entered the weight - loss field, especially boosted by the popularity of semaglutide, the relevant demand increased explosively, and at the same time, the problem of insufficient production capacity was exposed

Both peptides are designed for once-weekly subcutaneous dosing and possess extended half-lives (approximately 5 days for Tirzepatide and slightly longer for Retatrutide due to structural modifications)

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