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Renal cellular concentrations of GSH are maintained by both the intracellular synthesis and transport from outside the cells 39
doi: 10.1016/j.bbamcr.2018.02.010 48 YamamotoMKenslerTWMotohashiH
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Ferroptosis is driven by lipid peroxidation, relying on Fe 2+ -mediated Fenton reactions, and occurs in close association with dysregulation of the SLC7A11/GSH/GPX4 antioxidant system
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