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Any potential effects on menstrual patterns are secondary

In addition, the severe vomiting that can be induced by alcohol or that result from the complications associated with excessive ethanol ingestion lead to dehydration and decreased extracellular fluid volume, resulting in hypotension triggering a sympathetic nervous system response

In esophageal squamous cell carcinoma (ESCC), however, disruption of mitochondrial biogenesis through transcription factor A, mitochondrial (TFAM) downregulation strongly induces autophagy and promotes ESCC cancer growth, in line with the poor overall survival rate of ESCC patients with low expression of TFAM