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Both of the latter effects appear to be due to estradiol-mediated effects on development of the main olfactory system (17)

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demonstrated that GPX4 negatively regulates macrophage pyroptosis and septic lethality in mice by attenuating lipid peroxidation ( 5.3 Fungal and parasitic infections Emerging evidence suggests that ferroptosis represents a therapeutically exploitable pathway in both fungal and parasitic infections, with distinct intervention strategies demonstrating efficacy across different pathogen models