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Yes, the FDA approved Semaglutide as a treatment for chronic weight management in obese or overweight adults

In a different trial, Wachter et al., reported that supplementation with 2 g of l-carnitine given twice daily for a period of 3 months did not alter l-carnitine muscle levels [30]

Conclusion The findings of the current randomized parallel controlled trial provide compelling evidence that high-dosage LC supplementation (3 gr/day) in ICU septic patients holds significant potential