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Cullin3 ( Cul3 ) is a genome-wide significant ASD risk gene [26], whose haploinsufficiency contributes to a decreased neuronal dendritic growth and a decreased neuronal network activity [34]

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According to a study published in PubMed Central (National Institutes of Health), intravenous administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency