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The relevance of theobromine for the beneficial effects of cocoa consumption

The hepatic first-pass effect can be avoided to a great extent by use of sublingual tablets and transdermal preparations and to a lesser extent by use of rectal suppositories

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3.4 The target network and molecular docking with SIRT1 of GHK-Cu A flowchart of the drug target screening based on network pharmacology is shown in Figure 5A

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