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However, hormonal therapy may cause side effects such as weight gain, depression, acne, body hair, and irregular bleeding

Acutely, excess ROS engages cellular defenses, such as the NRF2 pathway and integrated stress response, allowing the cell to divert resources to mitigating oxidative stress

The MXD group serving as the positive control also developed darkened skin by this time (Fig

These modifications reduce binding to IGF binding proteins, extending its biological half-life relative to native IGF-1

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