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Important warning signs: If you experience severe, persistent abdominal pain (which may radiate to your back), with or without vomiting, seek urgent medical attention

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Similarly, in the STEP-HFpEF DM trial, which included 616 obese HFpEF patients with comorbid T2DM, once-weekly semaglutide 2.4 mg improved the KCCQ-CSS by 13.7 points versus 6.4 points with placebo at 52 weeks [103]

Its FDA-approved for people whose BMI is 30 or higher, or 27 and above with a weight-related medical condition

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