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Obesity In 1997, obesity was recognized as a global epidemic due to its unprecedented incidence and considerable health and socioeconomic consequences

W.BovijnS.BytyqiE.de FoozN.LuytenG.CasteleinM.et al

Interventions targeting microbiota are a prospective avenue for slowing disease progression

It is a sequence of 15 amino acids that acts like a biological repair signal, telling injured tissue to do what healthy tissue already knows how to do: build blood vessels, lay down collagen, close wounds, and calm inflammation

MOTS-c modulates the FOXO transcription factors and regulates cellular senescence, the state in which aged or damaged cells stop dividing but refuse to die, instead secreting a cocktail of inflammatory signals known as the senescence-associated secretory phenotype (SASP)