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All three increaselike SSRIsthe QTc interval, the first two of which also carry a risk of a serotonergic syndrome

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Szayna M, Doyle ME, Betkey JA, Holloway HW, Spencer RGS, Greig NH, et al

In protocol 2, we give 3.6 mM of NAC per hour for 10 hours beginning 2 hours after the 22 g APAP dose