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Here, we review the role and function of the GDH pathway in glutamate metabolism and we discuss the additional contributions of the pathway in chromatin regulation, nitrogen catabolite repression, ROS-mediated apoptosis, iron deficiency and sphingolipid-dependent actin cytoskeleton modulation in S.cerevisiae

However, factors such as aging, poor diet, stress, and environmental toxins can deplete glutathione levels, leading to oxidative stress and accelerated aging

A mitochondrial iron-responsive pathway regulated by DELE1

and Alangaden, G.J., Infect