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Second, to achieve precise clinical diagnosis of UC, more reasonable diagnostic criteria, such as noninvasive serological tests, gut microbiota testing, and detection of specific metabolites, should be developed and applied in clinical practice

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Consequently, Chiba et al 193 found that the oxygen consumption and brown adipose tissue (BAT) expression of ucp1, a thermogenesis-related gene, was significantly downregulated 18 hours after dapagliflozin treatment relative to the control group