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12.2 Pharmacodynamics The pharmacodynamic evaluations described below were in patients with type 2 diabetes mellitus who received once weekly subcutaneous injections of placebo or semaglutide injection over 12 weeks (semaglutide injection-treated patients were started on lower dosages and then titrated up to 1 mg once weekly)

Bao L, Yin J, Gao W, Wang Q, Yao W, Gao X (2018) A long-acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis partly through an FGF21-adiponectin-IL17A pathway

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The results showed that SCP2 significantly reversed the metabolic profile disorder in Alzheimers disease rats and played an important role in ameliorating A 25-35 -induced cognitive dysfunction, attenuating oxidative damage, and reducing A deposition in the hippocampus, which may provide new insight into the potential mechanisms of SCP2 treatment of AD (119)