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Methodologies for Future Research: Biomarkers and Neuroimaging Future preclinical studies in EAE models should incorporate a robust panel of biomarkers, such as neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP), to assess neuroaxonal damage and astrogliosis alongside clinical scores

Chao AM, Tronieri JS, Amaro A, Wadden TA

Indeed, we observed a higher degree of histological severity, in terms of microvascular inflammation, in biopsies positive for both Ab types

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Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D