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Primarily approved for type 2 diabetes management, it's also sometimes prescribed off-label for weight management

Most changes were not statistically different

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You can certainly make the case that the comparison group - insulin treatment - may put patients at higher cardiovascular risk because of the negative impact of elevated insulin levels

These medications have been studied extensively in clinical trials and have clear dosing escalation schedules, known side effect profiles, and consistent pharmacokinetics when delivered by injection