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During the occurrence of DOR, the deterioration of mitochondrial function and the intensification of oxidative stress provide a platform for signaling crosstalk among various PCD forms (Seli et al., 2019)

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In contrast, in a trial among more than 200 Chinese patients with various cancers who had peripheral neuropathy from previous chemotherapy, those who took ALC were more likely than those who took a placebo to have an improvement of at least one grade in their neuropathy