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They exhibited increased intraocular pressure and mydriasis, degeneration of retinal ganglion cells, optic nerve head excavation and reduction in optic nerve thickness, generalized severe irregularity of retinal vessels, faint presentation of choroidal vessels, and severe optic nerve disc atrophy

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It might be an old injury that never properly healed or a new, persistent ache

We typically recommend a 24 week break after 812 weeks on for chronic protocols the necessity isn't fully established, but it's a sensible conservative approach for long-term use