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In particular, anoxic tumor cells use lactate dehydrogenase A (LDHA) for lactate anabolism, which enters intercellular matrix through MCT4 and is taken up through MCT1 by aerobic tumor cells

Rare but Serious: Aseptic Meningitis Although uncommon, IVIG can occasionally trigger aseptic meningitis, an inflammation of the protective membranes surrounding the brain and spinal cord that is not caused by a bacterial infection

They are useful for treating deficits and increasing B12 consumption