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Spironolactone does this by reducing fluid volume in the blood vessels

10.1016/j.tips.2021.11.009 Summary Keywords neuroinflammation, oxidative stress, redox, epilepsy, mitochondria, NADPH oxidase Citation Fabisiak T and Patel M (2022) Crosstalk between neuroinflammation and oxidative stress in epilepsy

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When the storage capacity is exceeded, accumulated cholesterol crystallizes, leading to hepatocyte apoptosis and the release of cholesterol-crystal-laden lipid droplets (53)

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