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[4] [5] However, there is no established association between semaglutide and acquired hypothyroidism or clinically significant thyroid dysfunction affecting metabolism in humans

Lincoff, A

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The enhancement of viral infectivity could be attributed to the hypomethylation of STAT1, leading to a reduced binding of STAT1 to the interferon-stimulated response element and thus reduction of the expression of interferon-stimulated genes (ISGs), weakening the antiviral effects of interferon (78, 79)