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HW: Writing review & editing, Conceptualization
Liu J, Ren ZH, Qiang H, Wu J, Shen M, Zhang L, Lyu J
These groups received intravenous treatments of oridonin, orid-liposome, orid-liposome-MAL, and TLR2 pep-orid-liposome at a dosage of 5 mg/kg (equivalent to the active ingredient of oridonin), with PBS serving as the control, administered every other day
In vivo animal studies confirm these findings, showing that IGF-1 treatment accelerates functional recovery from Achilles tendon injury, improves tendon mechanical properties, and enhances collagen organization and composition in healing ligaments
Peptides offer high specificity and strong biological activity with relatively low toxicity
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