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doi: 10.1038/s41571-020-0352-8 279 HuinenZRHuijbersEJMvan BeijnumJRNowak-SliwinskaPGriffioenAW

The buffering of antioxidant species can be accomplished by reduced glutathione (GSH), that is also required for phase II detoxification in which endogenous and exogenous toxic metabolites are conjugated to GSH for their removal [10], [11]

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Antioxidants are nutrients (vitamins and minerals) as well as enzymes that are believed to play a role in preventing the development of such chronic diseases as cancer, heart disease, stroke, Alzheimer's disease,Rheumatoid arthritis, and cataracts