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Stimulation of whole blood cells from SZ patients with selective TLR agonists results in enhanced release of pro-inflammatory cytokines (including IL-1, IL-6, IL-8, and TNF-) (150), further supporting the role of TLRs in regulating neuroinflammation in schizophrenia
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Self-monitoring of blood glucose is particularly important for patients on concomitant insulin or sulfonylureas, as GLP-1 therapy may necessitate dose reductions of these medications to prevent hypoglycemia
