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The data sheets of both drugs indicate that they can be used in patients with mild or moderate renal failure, adjusting the dose and carefully monitoring renal function

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This can support broader patient access and more efficient global supply

IL-17 and IL-22 released by T H 17 can stimulate the formation of transforming growth factor- (TGF-), which promotes fibrosis by activating fibroblasts (Fabre et al., 2018)

Additionally, semaglutide slows gastric emptying, which means food moves more slowly from the stomach into the small intestine, contributing to improved glycaemic control and increased satiety