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Two robust regression LME models (package(nlme)(Pinheiro et al., 2023)) were estimated for each brain region to investigate the relationship between metabolite (GSH or GABA+) levels and diagnosis group, age, and sex, accounting for the random intercept of each participant

DIM (diindolylmethane) is a metabolite of a phytochemical called indole-3-carbinol found in cruciferous vegetables such as broccoli, brussels sprouts and cabbage

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These diseases all involve the critical role of ROS and mediated oxidative stress [32, 33]

However, on day 15, one patient experienced a serious complicationretinal detachment with proliferative vitreoretinopathynecessitating their removal from the trial