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These differences could explain, at least in part, some inconsistencies found among various studies, attributable to the different strains used

67 analyzed the metabolites of 13 C6-d-glucose-traced NPC cells by using gas chromatography/mass spectrometry (GC/MS), and found that glycolytic flux in LMP1-overexpressing cells was markedly increased by about 90% compared to that in LMP1-negative cells

In particular, miR-98 was under-expressed in samples from relapsed patient, strongly suggesting an important role for the miR-98 and EZH2 axis in NPC biology

Dimethyl fumarate (DMF), an FDAapproved NRF2 agonist for multiple sclerosis, indirectly inhibits NFB and has demonstrated antifibrotic effects by restoring redox homeostasis in aged IPF models (161)

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