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In liver biopsies obtained from NAFLD morbid obese patients undergoing bariatric surgery, miR-34a, apoptosis and acetylated p53 increase with disease severity, while sirtuin 1 (SIRT1) diminishes [15]
GSH was measured by HPLC (LC-10AT, Shimadzu, Japan) using a WondalSil C18 column (GL Sciences Inc., Japan) and a UV detector (SPD-20A, Shimadzu, Japan) at 210 nm
Uchida et al., 2013) and earlier in lung squamous cell carcinoma ( Even though only limited information is available regarding the regulation of GSTP1 by miRNAs, we believe that further investigations could contribute to the development of new therapeutic miRNA-based anticancer strategies
While this procedure offers a definitive cure, it permanently eliminates fertility, causing significant physical and psychological trauma to the patient [8]
