The accumulation of mAPP and A has been shown to increase mitochondrial fission and reduce fusion in hippocampal neurons, characterized by elevated levels of fission proteins Drp1 and Fis1, alongside decreased expression of fusion proteins Mitofusin 1, Mitofusin 2, and Optic Atrophy 1 (Reddy et al
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Gli acidi grassi a catena lunga, per essere bruciati, devono entrare nella matrice mitocondriale, ma non possono farlo da soli
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