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Nausea and vomiting can be particularly concerning for breast cancer patients undergoing chemotherapy, which often causes similar side effects

Australia In response to rising rates of overdose with MR paracetamol in Australia, and the increased risk of toxicity with MR paracetamol, Australia up-scheduled MR paracetamol from Pharmacy Only to Pharmacist Only in 2020 [Citation239]

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Additionally, DA quinones can be oxidized to aminochrome, whose redox-cycling leads to the generation of the superoxide radical and the depletion of cellular nicotinamide adenine dinucleotide phosphate-oxidase (NADPH), which ultimately forms the neuromelanin (Sulzer et al., 2000) known to be accumulated in the SNpc of the human brain (Ohtsuka et al., 2013, 2014