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Early clinical and preclinical data suggest benefits also in rheumatoid arthritis, osteoarthritis, osteoporosis, psoriasis, and hidradenitis suppurativa
Moreover, acetate and butyrate decrease the levels of reactive oxygen species (ROS), enhance the secretion of anti-inflammatory cytokine IL-10 and immunoregulatory factor IFN-, thereby further mitigating the inflammatory response (68)
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Patient Response Variability Individual patient responses to diabetes and obesity medications show considerable variability, often related to genetic factors, disease phenotype, and baseline characteristics
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