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Reduced intracellular methylation (HNMT pathway): HNMT histamine N methyltransferase employs SAMe, the methyl donor to counter histamine, particularly in the brain

This comprehensive review brings together multiple lines of evidence for the dysfunction of the glutamate system in mood disorders, including genetic, post-mortem and in vivo neuroimaging data

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Portion-controlled, protein- and fiber-rich options are increasingly marketed not as restrictive diet foods, but as tools to help individuals maintain nutritional adequacy within smaller eating windows