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An observational study of a cohort of 12 241 adults in the United States also used liver enzymes as a marker of MASLD and reported that MASLD (defined by elevated ALT, aspartate aminotransferase, or gamma-glutamyl transferase without evidence of an alternative explanation) was significantly less common in postmenopausal women using HRT compared to those not using HRT (OR 0.69

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The balance between efficacy and tolerability is therefore critical

All objects corresponding to the DTC and its cytonemes were grouped as one structure