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A 2012 gene expression analysis by Pickart and Margolina found that GHK-Cu modulated the activity of 4,048 human genes at a 50% or greater threshold, with notable upregulation of genes involved in DNA repair, ubiquitin/proteasome pathways, and anti-inflammatory responses [2]
The authors speculate that this could be due to off-label prescribing or individuals acquiring medications through non-medical routes such as online purchases
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10.1038/s41392-024-01951-9 34 MallaR.WangY.ChanW
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