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Extensive literature has demonstrated increases in oxidative stress post-exercise in horses (Mills et al., 1996

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Then, a vacuum is created to remove water by the sublimation process

Every doctor and patient needs to have an in-depth conversation about all of the nuances of risk or potential risks, Tchang adds

Clinical outcome: Mucositis, stomatitis Severe myelosuppression (anaemia, leukopenia, thrombocytopenia) Nephrotoxicity, hepatotoxicity Life-threatening infections, bleeding High-risk groups: Elderly Patients with renal impairment Patients on high-dose methotrexate (oncology use) Concomitant nephrotoxic drugs Advice: Avoid NSAIDs with high-dose methotrexate