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Int J Mol Sci 2020;21:4003.ArticlePubMedPMC 11

The cost for the 4 of the 10 mg vials is $499 for the first vial and $499 if renewed within 45 days or $699 if renewed after 45 days

Approximately 25% to 40% of people with T2D use insulin as part of their therapy to control their disease

Enhanced activity of IDO enzymes (IDO-1 and IDO-2) shifts tryptophan metabolism towards the kynurenine pathway, leading to increased concentrations of kynurenic acid (KYNA) within the CNS (216220)