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Another source of reducing equivalents comes from the selective transport of GSH, rather than GSSG, from the cytosol into the ER lumen

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For example, IFN- from Th1 cells inhibits Th2 differentiation, while IL-4 from Th2 cells inhibits Th1 differentiation.[ref] Thus, in healthy people without asthma or autoimmune diseases, there is a balance between the T1 and T2 immune response pathways