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Radiotherapy is another therapeutic option but is reserved for aggressive tumors that are not controlled by surgery or medical treatment due to the high risk of hypopituitarism and other complications

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Individual variability in treatment response is well-documented, with some patients achieving less than 5% body weight reduction despite proper use

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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Hasegawa K., Miwa S., Isomura K., Tsutsumiuchi K., Taniguchi H., Miwa J

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