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How Each Medication Works The key difference between these medications lies in their mechanisms of action

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Sebaceous Gland Anatomy and Physiology Aside from the free sebaceous glands on the vermilion lips (Fordyce granules), eyelids (meibomian glands), areolae (Montgomery tubercles), and labia minora and prepuce (Tyson glands), the duct of the sebaceous gland connects to the infundibulum of a hair follicle.[1] These glands are highly concentrated behind the ear and on the face, upper chest, and back, which happens to be the same distribution as acne vulgaris.[2] The major cells comprising sebaceous glands are sebocytes, and these cells disintegrate and release sebum via holocrine secretion