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Ongoing Support: What level of support regular check-ins, support groups, or coaching is provided

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Never start, stop, or change a medication without talking to a licensed clinician

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Researchers also evaluated total alcohol consumption, alcohol craving, body weight, laboratory biomarkers associated with alcohol use, metabolic measures, and safety outcomes

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Medline: ((obeses[All Fields] OR obesity[MeSH Terms] OR obesity[All Fields] OR obese[All Fields] OR obesities[All Fields] OR obesity s[All Fields] OR (overweight[MeSH Terms] OR overweight[All Fields] OR overweighted[All Fields] OR overweightness[All Fields] OR overweights[All Fields])) AND (orlistat[MeSH Terms] OR orlistat[All Fields] OR orlistat s[All Fields] OR (phentermine[MeSH Terms] OR phentermine[All Fields]) OR (topiramate[MeSH Terms] OR topiramate[All Fields] OR topiramate s[All Fields]) OR (naltrexone[MeSH Terms] OR naltrexone[All Fields] OR naltrexon[All Fields] OR naltrexone s[All Fields]) OR (bupropion[MeSH Terms] OR bupropion[All Fields] OR amfebutamone[All Fields] OR bupropion s[All Fields] OR bupropione[All Fields]) OR (liraglutid[All Fields] OR liraglutide[MeSH Terms] OR liraglutide[All Fields] OR liraglutide s[All Fields]) OR (semaglutide[Supplementary Concept] OR semaglutide[All Fields]) OR (tirzepatide[MeSH Terms] OR tirzepatide[All Fields]))) AND (randomizedcontrolledtrial[Filter]) Translations obesity: obeses[All Fields] OR obesity[MeSH Terms] OR obesity[All Fields] OR obese[All Fields] OR obesities[All Fields] OR obesitys[All Fields] overweight: overweight[MeSH Terms] OR overweight[All Fields] OR overweighted[All Fields] OR overweightness[All Fields] OR overweights[All Fields] orlistat: orlistat[MeSH Terms] OR orlistat[All Fields] OR orlistats[All Fields] phentermine: phentermine[MeSH Terms] OR phentermine[All Fields] topiramate: topiramate[MeSH Terms] OR topiramate[All Fields] OR topiramates[All Fields] naltrexone: naltrexone[MeSH Terms] OR naltrexone[All Fields] OR naltrexon[All Fields] OR naltrexones[All Fields] bupropion: bupropion[MeSH Terms] OR bupropion[All Fields] OR amfebutamone[All Fields] OR bupropions[All Fields] OR bupropione[All Fields] liraglutide: liraglutid[All Fields] OR liraglutide[MeSH Terms] OR liraglutide[All Fields] OR liraglutides[All Fields] semaglutide: semaglutide[Supplementary Concept] OR semaglutide[All Fields] tirzepatide: tirzepatide[MeSH Terms] OR tirzepatide[All Fields] Embase: (obesity/exp OR obesity OR overweight/exp OR overweight) AND (orlistat/exp OR orlistat OR phentermine/exp OR phentermine OR topiramate/exp OR topiramate OR naltrexone/exp OR naltrexone OR bupropion/exp OR bupropion OR liraglutide/exp OR liraglutide OR semaglutide/exp OR semaglutide OR tirzepatide/exp OR tirzepatide) AND [embase]/lim NOT ([embase]/lim AND [medline]/lim) AND (phase 3 clinical trial/de OR randomized controlled trial/de OR randomized controlled trial topic/de)

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Similarly, anyone with a history of pancreatitis should discuss the safety of these medications with a healthcare provider

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