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Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models

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Redox Control of Protein Function Although classical signaling pathways depend on macromolecular interactions, mild oxidants such as H 2 O 2 signal through chemical reactions with functional groups of target proteins, resulting in covalent protein modifications at the atomic level