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Cortese-Krott, M

The increased risk appears to be transient, declining after two years of TRT use, which the investigators attribute to a phenomenon called depletion of susceptibles. Our findings show that the use of TRT was associated with an increased risk of stroke, TIAs [transient ischaemic attack], or cardiac arrest during the first two years of use , noted Christel Renoux Testosterone may protect men from stomach inflammation, mouse study suggests

This is the same mechanism behind the rapid initial weight loss many people experience on low-carb diets, and it explains why the scale can move quickly in the first two weeks before fat loss has had time to accumulate meaningfully

If youre newly taking a GLP-1, what used to feel neutral to consume might now feel slightly off, or not worth it

Fasting GIP, GLP-1 and insulin were comparable in Gipr AP-KO animals and controls (Extended Data Fig