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And so weve discovered in our animal work and other folks have shown this, and weve done this also in our human studies, that by giving a GLP-1 agonist, yes, you could lose weight, and by that, could help the brain

So, Secher asked, does that mean that these are the only regions that are activated by GLP-1 receptor agonists? She and her team do not believe that this is the case, she said, because when you have interaction with one neuron, this can communicate to many other neurons in deeper layers of the brain. To test whether that was happening, her team used c-Fos, a protein that can be used as a marker for neuronal activation

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But it was far too sudden and really started getting worse after Covid

7 , e009609 (2018)