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Introduction When plants are exposed to various biotic and abiotic stresses, they exhibit characteristic increase in the production of reactive oxygen species (ROS) like singlet oxygen ( 1 O 2 ), superoxide (O 2 ), hydrogen peroxide (H 2 O 2 ) and hydroxyl radical (OH ) (Mittler et al., 2004)

Extensive research has shown that it may potentially aid in combating cardiovascular disease, neurodegenerative and disorders However, its therapeutic benefits have been limited by poor bioavailability, meaning that the body absorbs it in very low amounts when taken in traditional forms

Many superficial epithelial cells showed various stages of degeneration with derangement of organelles and excessive mucus shedding

( B ) Heatmap of GSH pathway metabolites intensity normalized by row as a z score from A549shNRF2-BIND-luc cells treated with 1 M A-485 for 24 h

Along with hydration and dermal collagen density