single-use devices should be discarded immediately after injection
Diabetes Care 34 , 21232129 (2011)
In animal studies, it was linked to reduced calorie intake, improved balance of gut bacteria, and increased fullness
M., Lehto, S., Ronnemaa, T., Pyorala, K
What the new mechanism is: GLP-1 : appetite regulation, improved glucose control GIP : incretin effects that may augment metabolic benefits Glucagon receptor activity : potentially influences energy expenditure and fat metabolism (while requiring careful balancing of tolerability and metabolic effects) What results look like (so far): Phase 2 (48 weeks) published in NEJM showed substantial mean weight reductions (with higher doses showing very large effects)