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Description

Genetic variations in the GLP-1 receptor pathway, FTO gene (appetite regulation), MC4R gene (energy homeostasis), and GIPR signaling may influence baseline metabolism, satiety signaling, and weight loss trajectory

doi: 10.1101/gad.1097103 28 MoensKFlamezDSchravendijk VanCLingZPipeleersDSchuitF

Therefore, modulating the gut microbiota via dietary interventions, especially increasing the abundance of butyrate-producing bacteria, may offer a feasible strategy to counteract T2D and associated metabolic abnormalities 11