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Patients were included if they had baseline bilateral pain radiographs demonstrating Kellgren and Lawrence grades of 1 to 3, as well as at least 2 years of follow-up before the initiation of GLP-1RA therapy for the sake of comparisons between groups

Lewy bodies, once thought to be mere markers, are now considered active participants in disease propagation due to their interaction with endolysosomal and mitochondrial pathways (Dorsey et al., 2024

Both can be supplemented safely alongside GLP-1 medications, but should be taken at least 4 hours away from levothyroxine to avoid absorption interference

Strict quality controls ensure that Carni-Fortan is a reliable component of a need-based nutrition plan