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Because it degrades in blood in a pathway involving amino-peptidases, it may not be suitable for people who take medications that inhibit or are metabolized by peptidases (e.g., captopril, a treatment for hypertension).4 Also, based on what we know about other therapeutic peptides, we would say DSIP is contraindicated for women who are pregnant or breastfeeding as well as people with a personal history of cancer

CNS Drugs 27:505514

Instead, it may offer slow, consistent reinforcement of the bodys natural repair and recovery mechanisms

Watch-outs to know: Anecdotal reports from those who use unregulated MOTS-c peptides include side effects such as heart palpitations, insomnia, fever, and general injection-site reactions

Antioxidant enzyme activation Studies in aging rats found that epitalon increased the activities of antioxidant enzymes including superoxide dismutase, glutathione peroxidase, and glutathione-S-transferase