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Vitamin B6, zinc, magnesium and selenium may also influence antioxidant protection and pathway function

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All dosages were generally well tolerated, with gastrointestinal symptoms being the most frequently reported adverse effect

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The mechanism of action includes binding to the GHS-R1a receptor, activation of the Gq/11 protein-dependent signaling pathway and an increase in the intracellular concentration of calcium ions in somatotropes